860 research outputs found

    Comparison between the Use of LMAā„¢ and SLIPAā„¢ in Patients Undergoing Minor Surgeries.

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    Supraglottic airway devices have been used as safe alternatives to endotracheal intubation in appropriate types of surgery. This was a prospective, randomised, single blind study comparing the use of LMAā„¢ and SLIPAā„¢ in terms of ease of insertion, haemodynamic changes and occurrence of adverse effects (e.g. blood stains on the device upon removal and sore throat). A total of 62 ASA I or II patients, aged between 18 to 70 years were recruited for this study. Patients were randomised into two groups; LMAā„¢ and SLIPAā„¢ group. Following induction of anaesthesia, an appropriate sized LMAā„¢ or SLIPAā„¢ was inserted after ensuring adequate depth of anaesthesia. Anaesthesia was maintained with oxygen, nitrous oxide and sevoflurane. The ease of insertion was graded and haemodynamic changes were recorded at 2 minute intervals up to 10 minutes after insertion of the airway devices. The presence of blood stains upon airway device removal at the end of surgery and incidence of sore throat was also recorded. No difficult insertion was experienced in either of these devices. Insertion was either easy [LMAā„¢ 87.1% versus SLIPAā„¢ 80.6% (p = 0.49)] or moderate [LMAā„¢ 12.9% versus SLIPAā„¢ 19.4% (p = 0.16)]. Throughout the study period, the haemodynamic changes that occurred in both groups were not statistically different. Traces of blood were noted on the surface of the device in 9.7% of patients in the SLIPAā„¢ group versus 6.5% of patients in the LMAā„¢ group. The incidence of sore throat was recorded in 12.9% versus 19.4% of patients in the SLIPAā„¢ and the LMAā„¢ groups respectively. These findings were not statistically significant. In conclusion, this study showed no significant differences between the use of LMAā„¢ and SLIPAā„¢ in terms of ease of insertion, haemodynamic changes and adverse effects in patients undergoing minor surgical procedures

    Arsenic accumulation in rice (Oryza sativa L.) varieties of Bangladesh: A glass house study

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    A glass house study was conducted to investigate the accumulation of arsenic in tissues of five widely cultivated rice (Oryza sativa L.) varieties of Bangladesh namely BRRI dhan 28, BRRI dhan 29, BRRI dhan 35, BRRI dhan 36, BRRI hybrid dhan 1. Arsenic concentrations were measured in straw, husk and brown and polish rice grain to see the differential accumulation of arsenic among the rice varieties. The results showed that the concentrations of arsenic in different parts of all rice varieties increased significantly (p BRRI dhan 35 > BRRI dhan 36 > BRRI dhan 29 > BRRI hybrid dhan 1. The order of arsenic contents in tissues of rice was: straw > husk > brown rice grain > polish rice grain. Ā© 2007 Springer Science+Business Media B.V

    Evaluation of postharvest quality of edible coated mandarin at ambient storage

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    An experiment was conducted to assess the influence of edible coatings on postharvest quality of mandarin during 20 days of ambient storage. Sorted fruits were washed; fruit surface water was removed and then coated with 100% liquid paraffin wax, 0.5% chitosan, 1.0% chitosan, 1.5% chitosan, and 100% coconut oil. After coating, fruit surface was air dried and kept at ambient condition (25Ā±3 Ā°C, 60ā€“70% RH) and analyzed periodically for weight loss, respiration rate, firmness, decay incidence, TSS, pH, ascorbic acid content, and sensory properties. The results revealed that coconut oil had immense effect on the reduction of the weight loss and respiration rate and preserved firmness, total soluble solids, ascorbic acid, total sugar and reducing sugar and no incidence of moulds & their growth was found up to 16 days of storage.Int. J. Agril. Res. Innov. & Tech. 8 (1): 18-25, June, 201

    Toxicity bioassay of chlorpyrifos on some local fish species of northern Bangladesh

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    Four fish species namely, stinging catfish (Heteropneustes fossilis), spotted snakehead (Channa punctatus), climbing perch (Anabas testudineus) and tangra (Batasio tengana) were exposed to various concentrations of chlorpyrifos (Expert 20 EC) to investigate the mortality rate of fish species and the toxicity level of the pesticide. The LC50 values of chlorpyrifos on these fish species were 23.10, 20.32, 16.61 and 13.94 ppm, respectively at 96 hours of exposure. Among these results, it is clear that the lethal concentration is varying species to species because their strengths are different. During the experiments, some water quality parameters such as temperature, pH, dissolved oxygen, total dissolved solids and electrical conductivity were also analyzed. The temperature values remained within the ranges of 17-20Ā°C and the pH was 6.64-7.30. Fish behaved irregular and erratic movements followed by hyper excitability, loss of balance and settling to the bottom of the test chamber. At higher concentration of chlorpyrifos, alterations in physiological and behavioural responses especially erratic swimming, gulping, mucus secretion, increased opercular movement and profuse emission of mucus all above the body were observed during the primary stages of contact after which it became occasional. Int. J. Agril. Res. Innov. & Tech. 9 (1): 42-47, June, 201

    Perceived change in tobacco use and its associated factors among older adults residing in rohingya refugee camps during the covid-19 pandemic in bangladesh

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    This study explored the perceived change in tobacco use during the COVID-19 pandemic and its associated factors among older adults residing in Rohingya refugee camps, also referred to as Forcibly Displaced Myanmar Nationals in Bangladesh. The study followed a cross-sectional design and was conducted in October 2020 among 416 older adults aged 60 years and above. A purposive sampling technique was applied to identify eligible participants, and face-to-face interviews were conducted using a pre-tested semi-structured questionnaire to collect the data. Participants were asked if they noted any change in their tobacco use patterns (smoking or smokeless tobacco) during the COVID-19 pandemic compared to pre-pandemic. Binary logistic regression models determined the factors associated with the perceived change in tobacco use. More than one in five participants (22.4%) were current tobacco users, of whom 40.8% reported a perceived increase in tobacco use during the COVID-19 pandemic. Adjusted analysis revealed that participants who were concerned about COVID-19 had significantly (p < 0.05) lower odds of perceived increase in tobacco use (aOR = 0.22, 95% CI: 0.06ā€“0.73), while older adults who were overwhelmed by COVID-19 (aOR = 0.26, 95% CI: 0.06ā€“1.18) and communicated less frequently with others during the pandemic than before (aOR = 0.19, 95% CI: 0.03ā€“1.20) had marginally significantly (p < 0.1) lower odds of perceived increase in tobacco use during this pandemic. Relevant stakeholders, policymakers, and practitioners need to focus on strengthening awareness-raising initiatives as part of an emergency preparedness plan to control tobacco use during such a crisis period

    Enhancement of biogas generation in up-flow sludge blanket (UASB) bioreactor from palm oil mill effluent (POME)

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    Ā© 2019 The Authors. Published by Elsevier Ltd. There are numerous different sorts of pre-treatment technique have been utilized with a few impediments regarding supportable natural administration in anaerobic assimilation for improvement of biogas generation. Albeit corrosive and salt pretreatment have a huge impact on the corruption of biomass, these techniques have some negative effects on the condition because of their perilous nature, while the enzymatic pre-treatment is more environmentally friendly. In this investigation is to streamline the biogas generation by enzymatic pre-treatment from Palm Oil Mill Effluent (POME) with assessing the improved biogas creation in a pilot scale bioreactor. It is to concentrate coordinate utilization of protein as enzymatic pre-treatment on POME to the improved generation of biogas. Proficiency of privately manufactured chemical with Up-flow Sludge Blanket (UASB) has not been researched in pilot scale previously. In this examination proficiency of COD expulsion and aggregate methane emanation is explored through pilot scale UASB bioreactor from POME through the application of enzyme and reviewed a study with the discussion

    Understanding experiences of Aboriginal and/or Torres Strait Islander patients at the emergency departments in Australia

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    Objectives: The present study describes the experiences of Aboriginal and/or Torres Strait Islander patients and the factors that shaped their experiences of ED visits in regional settings. Methods: This is a qualitative descriptive study. We conducted semi-structured in-depth interviews with Aboriginal and/or Torres Strait Islander patients who used the ED services at three hospitals in New South Wales, Northern Territory and South Australia. We coded the collected data and analysed them using a thematic analysis technique. Results: A total of 33 Aboriginal and/or Torres Strait Islander patients participated. Analyses of their experiences revealed four themes, which included: (i) patients' waiting times in ED; (ii) cultural determinants of health; (iii) treatment services; and (iv) safety, security and privacy. Conclusions: A holistic approach and a robust hospital commitment to address cultural needs while considering overall health, social and emotional wellbeing, will enhance Aboriginal and/or Torres Strait Islander patients' satisfaction for ED visits

    A Novel, ā€œDouble-Clampā€ Binding Mode for Human Heme Oxygenase-1 Inhibition

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    The development of heme oxygenase (HO) inhibitors is critical in dissecting and understanding the HO system and for potential therapeutic applications. We have established a program to design and optimize HO inhibitors using structure-activity relationships in conjunction with X-ray crystallographic analyses. One of our previous complex crystal structures revealed a putative secondary hydrophobic binding pocket which could be exploited for a new design strategy by introducing a functional group that would fit into this potential site. To test this hypothesis and gain further insights into the structural basis of inhibitor binding, we have synthesized and characterized 1-(1H-imidazol-1-yl)-4,4-diphenyl-2-butanone (QC-308). Using a carbon monoxide (CO) formation assay on rat spleen microsomes, the compound was found to be āˆ¼15 times more potent (IC50ā€Š=ā€Š0.27Ā±0.07 ĀµM) than its monophenyl analogue, which is already a potent compound in its own right (QC-65; IC50ā€Š=ā€Š4.0Ā±1.8 ĀµM). The crystal structure of hHO-1 with QC-308 revealed that the second phenyl group in the western region of the compound is indeed accommodated by a definitive secondary proximal hydrophobic pocket. Thus, the two phenyl moieties are each stabilized by distinct hydrophobic pockets. This ā€œdouble-clampā€ binding offers additional inhibitor stabilization and provides a new route for improvement of human heme oxygenase inhibitors
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